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氨鲁米特 Aminoglutethimide
性 状:白色或乳白色细的结晶性粉末。极微溶于水,易溶于许多有机溶剂。遇强酸形成水溶性盐。其0.1%稀甲醇(1:20)溶液的pH值为6.2-7.3。
用 途:本品能抑制肾上腺皮质激素中甾体激素的合成,同时能通过抑制芳香化酶阻止肾上腺外组织中雌激素的合成,用于治疗晚期乳腺癌及术后乳腺癌。本品并可用于皮质醇增多症的治疗。
Appearance : A white or creamy-white, fine, crystalline powder. Very slightly soluble in water; readily soluble in most organic solvents. It forms water-soluble salts with strong acids. The pH of a 0.1%solution in dilute methyl alcohol (1 in 20) is between 6.2 and 7.3..
Use: It is an inhibitor of adrenocortical steroid synthesis and also adrenal estrogen synthesis by inhititing aromatization enzyme. It is indicated in the treatment of advanced breast cancer and breast cancer after surgery. It is also used to decrease the adrenal secretion of cortisol.
CAS number:125-84-8
molecular formula: : C13H16N2O2

molecular weight:232.2783

Standard: USP

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